产品名称
STX4 Rabbit Polyclonal Antibody (Center)
别名
Syntaxin-4, Renal carcinoma antigen NY-REN-31, STX4, STX4A
Human Gene ID
NP_004595.2
Human Swissprot No.
Q12846
特异性
This STX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of human STX4.
背景介绍
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
组织表达
Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
细胞定位
Cell membrane {ECO:0000250|UniProtKB:Q08850}; Single-pass type IV membrane protein. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q08850}. Note=Localizes to neurite tips in neuronal cells. {ECO:0000250|UniProtKB:Q08850}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
