BD-PB1823-mouse BAD Rabbit Polyclonal Antibody (Center S112/S111/Y113)-现货抗体产品库武汉枢密脑科学技术有限公司

mouse BAD Rabbit Polyclonal Antibody (Center S112/S111/Y113)

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产品基本信息

产品货号

BD-PB1823

产品名称

mouse BAD Rabbit Polyclonal Antibody (Center S112/S111/Y113)

别名

Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bad, Bbc6

类别

常规抗体

推荐应用

反应种属

Mouse

Human Swissprot No.

Q61337

Mouse Gene ID

NP_031548.1

特异性

This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD.

稀释度

WB~~1:1000

预测分子量

22kDa

同种型

Rabbit Ig

背景介绍

BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

细胞定位

Mitochondrion outer membrane. Cytoplasm. Note=Colocalizes with HIF3A isoform 2 in the cytoplasm (PubMed:21546903). Upon phosphorylation, locates to the cytoplasm.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-mouse BAD Antibody at 1:1000 dilution Lane 1: A20 whole cell lysate Lane 2: C2C12 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 22 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Mouse BAD Antibody (Center S112/S111/Y113) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BAD antibody detected the BAD protein (arrow).