产品名称
AGTRAP Rabbit Polyclonal Antibody (C-term)
别名
Type-1 angiotensin II receptor-associated protein, AT1 receptor-associated protein, AGTRAP, ATRAP
Human Gene ID
NP_001035284.1;NP_001035285.1;NP_001035286.1;NP_001035287.1;NP_065083.3
Human Swissprot No.
Q6RW13
特异性
This AGTRAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-159 amino acids from the C-terminal region of human AGTRAP.
背景介绍
This gene encodes a transmembrane protein localized to the
plasma membrane and perinuclear vesicular structures. The gene
product interacts with the angiotensin II type I receptor and
negatively regulates angiotensin II signaling. Alternative splicing
of this gene generates multiple transcript variants encoding
different isoforms.
组织表达
Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.
细胞定位
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
