产品名称
SSX3 Rabbit Polyclonal Antibody (Center)
别名
Protein SSX3, Cancer/testis antigen 53, CT53, SSX3
Human Gene ID
NP_066294.1
Human Swissprot No.
Q99909
特异性
This SSX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the Central region of human SSX3.
背景介绍
The product of this gene belongs to the family of highly
homologous synovial sarcoma X (SSX) breakpoint proteins. These
proteins may function as transcriptional repressors. They are also
capable of eliciting spontaneously humoral and cellular immune
responses in cancer patients, and are potentially useful targets in
cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have
been involved in the t(X;18) translocation characteristically found
in all synovial sarcomas. This gene appears not to be involved in
this type of chromosome translocation. Two transcript variants
encoding distinct isoforms have been identified for this gene.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
