产品名称
HAUS8 Rabbit Polyclonal Antibody (N-term)
别名
HAUS augmin-like complex subunit 8, HEC1/NDC80-interacting centrosome-associated protein 1, Sarcoma antigen NY-SAR-48, HAUS8, HICE1
Human Gene ID
NP_001011699.1;NP_219485.1
Human Swissprot No.
Q9BT25
特异性
This HAUS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human HAUS8.
背景介绍
HAUS8 is 1 of 8 subunits of the 390-kD human augmin
complex, or HAUS complex. The augmin complex was first identified
in Drosophila, and its name comes from the Latin verb 'augmentare,'
meaning 'to increase.' The augmin complex is a microtubule-binding
complex involved in microtubule generation within the mitotic
spindle and is vital to mitotic spindle assembly (Goshima et al.,
2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed
19369198]).
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
