产品名称
SS18L1 Rabbit Polyclonal Antibody (Center)
别名
Calcium-responsive transactivator, SS18-like protein 1, SYT homolog 1, SS18L1, CREST, KIAA0693
Human Gene ID
NP_945173.1
Human Swissprot No.
O75177
特异性
This SS18L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human SS18L1.
背景介绍
Synovial sarcomas occur most frequently in the extremities
around large joints. More than 90% of cases have a recurrent and
specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which
the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to
the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or
SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to
SS18.
组织表达
Ubiquitous; with lowest levels in spleen.
细胞定位
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to nuclear bodies Colocalizes with SGO1 at kinetochore (By similarity).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
