产品名称
MTL5 Rabbit Polyclonal Antibody (C-term)
别名
Tesmin, Metallothionein-like 5, testis-specific, Testis-specific metallothionein-like protein, MTL5
Human Gene ID
NP_001034745.1;NP_004914.2
Human Swissprot No.
Q9Y4I5
特异性
This MTL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-368 amino acids from the C-terminal region of human MTL5.
背景介绍
Metallothionein proteins are highly conserved
low-molecular-weight cysteine-rich proteins that are induced by and
bind to heavy metal ions and have no enzymatic activity. They may
play a central role in the regulation of cell growth and
differentiation and are involved in spermatogenesis. This gene
encodes a metallothionein-like protein which has been shown to be
expressed differentially in mouse testis and ovary. Two transcript
variants encoding different isoforms have been found for this gene.
组织表达
Expressed specifically in testis.
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:Q9WTJ6}. Nucleus {ECO:0000250|UniProtKB:Q9WTJ6}. Note=Predominantly localized to the cytoplasm. Translocates from the cytoplasm to the nucleus in the G2/M transition upon treatment with cadmium, cobalt or zinc {ECO:0000250|UniProtKB:Q9WTJ6}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
