产品名称
SP7 Rabbit Polyclonal Antibody
蛋白名称
Transcription factor Sp7 (Zinc finger protein osterix)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8TDD2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TDD2/entry
Mouse Swissprot No.
Q8VI67
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VI67
免疫原
Synthesized peptide derived from human protein . at AA range: 280-360
特异性
SP7 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010],
组织表达
Restricted to bone-derived cell.
功能
function:Transcriptional activator essential for osteoblast differentiation. Binds to Sp1 and EKLF consensus sequences and to other G/C-rich sequences.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
