产品名称
GALNT9 Rabbit Polyclonal Antibody (Center)
别名
Polypeptide N-acetylgalactosaminyltransferase 9, Polypeptide GalNAc transferase 9, GalNAc-T9, pp-GaNTase 9, Protein-UDP acetylgalactosaminyltransferase 9, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9, GALNT9
Human Gene ID
NP_001116108.1;NP_068580.2
Human Swissprot No.
Q9HCQ5
特异性
This GALNT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the Central region of human GALNT9.
稀释度
WB~~1:1000;IHC-P~~1:100
背景介绍
This gene encodes a member of the
UDP-N-acetyl-alpha-D-galactosamine:polypeptide
N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi
apparatus by catalyzing the transfer of GalNAc to serine and
threonine residues on target proteins. They are characterized by an
N-terminal transmembrane domain, a stem region, a lumenal catalytic
domain containing a GT1 motif and Gal/GalNAc transferase motif, and
a C-terminal ricin/lectin-like domain. GalNAc-Ts have different,
but overlapping, substrate specificities and patterns of
expression. This gene is expressed specifically in the brain, with
highest expression in the cerebellum. Multiple transcript variants
encoding different isoforms have been found for this gene.
组织表达
Specifically expressed in brain. Not expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. In brain, it is expressed in cerebellum, frontal lobe, temporal lobe, putamen and spinal cord, weakly expressed in cerebral cortex. Not expressed in medulla and occipital pole
细胞定位
Golgi apparatus membrane; Single- pass type II membrane protein
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
