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CELA1 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号
BD-PB1688
产品名称
CELA1 Rabbit Polyclonal Antibody (N-term)
别名
Chymotrypsin-like elastase family member 1, Elastase-1, Pancreatic elastase 1, CELA1, ELA1
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001962.3
Human Swissprot No.
Q9UNI1
特异性
This CELA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CELA1.
稀释度
WB~~1:1000
预测分子量
28kDa
同种型
Rabbit Ig
背景介绍
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.
组织表达
Basal layers of epidermis (at protein level). Not expressed in the pancreas.
细胞定位
Secreted.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-CELA1 Antibody (N-term) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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