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HMGB4 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1679
产品名称
HMGB4 Rabbit Polyclonal Antibody (Center)
别名
High mobility group protein B4, HMGB4
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_660206.2
Human Swissprot No.
Q8WW32
特异性
This HMGB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the Central region of human HMGB4.
稀释度
WB~~1:1000
预测分子量
22kDa
同种型
Rabbit Ig
背景介绍
High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. Chromosome
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of lysates from Jurkat, PC-3 cell line (from left to right), using HMGB4 Antibody (Center). BD-PB1679 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

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