产品名称
INF2 Rabbit Polyclonal Antibody (Center)
别名
Inverted formin-2, HBEBP2-binding protein C, INF2, C14orf151, C14orf173
Human Gene ID
NP_001026884.3;NP_071934.3;NP_116103.1
Human Swissprot No.
Q27J81
特异性
This INF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human INF2.
背景介绍
This gene represents a member of the formin family of
proteins. It is considered a diaphanous formin due to the presence
of a diaphanous inhibitory domain located at the N-terminus of the
encoded protein. Studies of a similar mouse protein indicate that
the protein encoded by this locus may function in polymerization
and depolymerization of actin filaments. Mutations at this locus
have been associated with focal segmental glomerulosclerosis 5.
组织表达
Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells
细胞定位
Cytoplasm, perinuclear region
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
