产品名称
SNX21 Rabbit Polyclonal Antibody (Center)
别名
Sorting nexin-21, Sorting nexin L, SNX-L, SNX21, C20orf161, SNXL
Human Gene ID
NP_001036098.1;NP_219489.1;NP_690857.1
Human Swissprot No.
Q969T3
特异性
This SNX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-236 amino acids from the Central region of human SNX21.
背景介绍
This gene encodes a member of the sorting nexin family.
Members of this family contain a phox (PX) domain, which is a
phosphoinositide binding domain, and are involved in intracellular
trafficking. This protein does not contain a coiled coil region,
like some family members. The specific function of this protein has
not been determined. Multiple transcript variants encoding distinct
isoforms have been identified for this gene.
组织表达
Highly expressed in fetus liver, but only weakly expressed in brain, skeleton muscle, smooth muscle, and cardiac muscle, kidney, and adrenal gland.
细胞定位
Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q3UR97}; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane {ECO:0000250|UniProtKB:Q3UR97}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q3UR97}; Cytoplasmic side {ECO:0000250|UniProtKB:Q3UR97}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.