产品名称
MTMR14 Rabbit Polyclonal Antibody (N-term)
别名
Myotubularin-related protein 14, 313-, HCV NS5A-transactivated protein 4 splice variant A-binding protein 1, NS5ATP4ABP1, hJumpy, MTMR14, C3orf29
Human Gene ID
NP_001070993.1;NP_001070994.1;NP_071930.2
Human Swissprot No.
Q8NCE2
特异性
This MTMR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human MTMR14.
背景介绍
This gene encodes a myotubularin-related protein. The
encoded protein is a phosphoinositide phosphatase that specifically
dephosphorylates phosphatidylinositol 3,5-biphosphate and
phosphatidylinositol 3-phosphate. Mutations in this gene are
correlated with autosomal dominant centronuclear myopathy.
Alternate splicing results in multiple transcript variants. A
pseudogene of this gene is found on chromosome 18.
组织表达
Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas
细胞定位
Cytoplasm. Note=Found in reticular structures and plasma membrane ruffles Concentrated near the nucleus
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.