产品名称
ARID5B Rabbit Polyclonal Antibody (Center)
别名
AT-rich interactive domain-containing protein 5B, ARID domain-containing protein 5B, MRF1-like protein, Modulator recognition factor 2, MRF-2, ARID5B, DESRT, MRF2
Human Gene ID
NP_001231567.1;NP_115575.1
Human Swissprot No.
Q14865
特异性
This ARID5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human ARID5B.
背景介绍
DNA-binding protein that binds to the 5'-AATA[CT]-3' core sequence. Probably acts as a transcription regulator. Represses the cytomegalovirus enhancer. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may act as a regulator of smooth muscle cell differentiation and proliferation. May be involved in lipid stores.
组织表达
Widely expressed, including in liver (at protein level).
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355}.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.