产品名称
HIST1H2AB Rabbit Polyclonal Antibody (N-term)
别名
Histone H2A type 1-B/E, Histone H2A2, Histone H2A/a, Histone H2A/m, HIST1H2AB, H2AFM
Human Gene ID
NP_003504.2;NP_066390.1
Human Swissprot No.
P04908
特异性
This HIST1H2AB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-38 amino acids from the N-terminal region of human HIST1H2AB.
背景介绍
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. This structure consists of approximately 146 bp of DNA
wrapped around a nucleosome, an octamer composed of pairs of each
of the four core histones (H2A, H2B, H3, and H4). The chromatin
fiber is further compacted through the interaction of a linker
histone, H1, with the DNA between the nucleosomes to form higher
order chromatin structures. This gene is intronless and encodes a
member of the histone H2A family. Transcripts from this gene lack
polyA tails; instead, they contain a palindromic termination
element. This gene is found in the large histone gene cluster on
chromosome 6p22-p21.3.
细胞定位
Nucleus. Chromosome.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
