BD-PB1631-KDM6B Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

KDM6B Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB1631

产品名称

KDM6B Rabbit Polyclonal Antibody (N-term)

别名

Lysine-specific demethylase 6B, 11411-, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Lysine demethylase 6B, KDM6B, JMJD3, KIAA0346

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_001073893.1

Human Swissprot No.

O15054

特异性

This KDM6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-195 amino acids from the N-terminal region of human KDM6B.

稀释度

WB~~1:1000

预测分子量

177kDa

同种型

Rabbit Ig

背景介绍

Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

细胞定位

Nucleus.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-KDM6B Antibody (N-term) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 177 kDa Blocking/Dilution buffer: 5% NFDM/TBST.