BD-PB1620-KLHL12 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

KLHL12 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB1620

产品名称

KLHL12 Rabbit Polyclonal Antibody (C-term)

别名

Kelch-like protein 12, CUL3-interacting protein 1, DKIR homolog, hDKIR, KLHL12, C3IP1

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_067646.1

Human Swissprot No.

Q53G59

特异性

This KLHL12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human KLHL12.

稀释度

WB~~1:1000

预测分子量

63kDa

同种型

Rabbit Ig

背景介绍

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.

组织表达

Ubiquitously expressed. Highly expressed in testis and at lower levels in the submandibular salivary gland

细胞定位

Cytoplasmic vesicle, COPII-coated vesicle

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

KLHL12 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).

KLHL12 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).