BD-PB1606

ASB2 Rabbit Polyclonal Antibody (N-term)

Ankyrin repeat and SOCS box protein 2, ASB-2, ASB2

常规抗体

WB

Human

NP_001189358.1;NP_057234.2

Q96Q27

This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.

WB~~1:1000

70kDa

Rabbit Ig

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

[Isoform 1]: Expressed in muscle cells.

Cytoplasm, cytoskeleton, stress fiber

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.