产品名称
GCNT1 Rabbit Polyclonal Antibody (Center)
别名
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT, Core 2 GNT, GCNT1, NACGT2
Human Gene ID
NP_001091102.1;NP_001091103.1;NP_001091104.1;NP_001091105.1;NP_001481.2
Human Swissprot No.
Q02742
特异性
This GCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human GCNT1.
背景介绍
This gene is a member of the
beta-1,6-N-acetylglucosaminyltransferase gene family. It is
essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc
structures and the core 2 O-glycan branch. The gene coding this
enzyme was originally mapped to 9q21, but was later localized to
9q13. Multiple alternatively spliced variants, encoding the same
protein, have been identified.
组织表达
Highly expressed in activated T-lymphocytes and myeloid cells
细胞定位
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Also detected in the trans-Golgi network
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.