产品名称
PTDSS1 Rabbit Polyclonal Antibody (C-term)
别名
Phosphatidylserine synthase 1, PSS-1, PtdSer synthase 1, Serine-exchange enzyme I, PTDSS1, KIAA0024, PSSA
Human Gene ID
NP_055569.1
Human Swissprot No.
P48651
特异性
This PTDSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human PTDSS1.
背景介绍
Phosphatidylserine (PS) accounts for 5 to 10% of cell
membrane phospholipids. In addition to its role as a structural
component, PS is involved in cell signaling, blood coagulation, and
apoptosis. PS is synthesized by a calcium-dependent base-exchange
reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that
exchange L-serine for the polar head group of phosphatidylcholine
(PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al.,
2001 [PubMed 11084049]).
细胞定位
Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q99LH2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q99LH2}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250|UniProtKB:Q99LH2}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.