产品名称
DHX30 Rabbit Polyclonal Antibody (N-term)
别名
Putative ATP-dependent RNA helicase DHX30, DEAH box protein 30, DHX30, DDX30, KIAA0890
Human Gene ID
NP_055781.2;NP_619520.1
Human Swissprot No.
Q7L2E3
特异性
This DHX30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human DHX30.
背景介绍
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this DEAD box
protein family are believed to be involved in embryogenesis,
spermatogenesis, and cellular growth and division. This gene
encodes a member of this family. The encoded protein has 97%
sequence identity with the mouse HELG protein. Alternatively
spliced transcript variants encoding distinct isoforms have been
found for this gene.
细胞定位
Cytoplasm. Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids (PubMed:16825194, PubMed:25683715). Relocalizes to stress granules upon heat stress (PubMed:29100085).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
