产品名称
P2RX6 Rabbit Polyclonal Antibody (Center)
别名
P2X purinoceptor 6, P2X6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1, P2RX6, P2RXL1, P2X6
Human Gene ID
NP_001153026.1;NP_005437.2
Human Swissprot No.
O15547
特异性
This P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
背景介绍
The protein encoded by this gene belongs to the family of
P2X receptors, which are ATP-gated ion channels and mediate rapid
and selective permeability to cations. This gene is predominantly
expressed in skeletal muscle, and regulated by p53. The encoded
protein is associated with VE-cadherin at the adherens junctions of
human umbilical vein endothelial cells. Alternative splicing
results in multiple transcript variants. A related pseudogene,
which is also located on chromosome 22, has been identified.
组织表达
Expressed predominantly in skeletal muscle.
细胞定位
Membrane; Multi-pass membrane protein.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
