产品名称
NKAP Rabbit Polyclonal Antibody
蛋白名称
NF-kappa-B-activating protein
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8N5F7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N5F7/entry
Mouse Swissprot No.
Q9D0F4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D0F4
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q4V7C9
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
NKAP Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010],
组织表达
B-cell,Cervix,Epithelium,Hepatocyte,Placenta,Small intestine,Testis,
功能
function:Regulator of TNF and IL-1 induced NF-kappa-B activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the UPF0396 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
