BD-PB1591-EYA2 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

EYA2 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB1591

产品名称

EYA2 Rabbit Polyclonal Antibody (Center)

别名

Eyes absent homolog 2, EYA2, EAB1

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_005235.3;NP_742108.2

Human Swissprot No.

O00167

特异性

This EYA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the Central region of human EYA2.

稀释度

WB~~1:1000

预测分子量

59kDa

同种型

Rabbit Ig

背景介绍

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined.

组织表达

Highest expression in muscle with lower levels in kidney, placenta, pancreas, brain and heart

细胞定位

Cytoplasm. Nucleus Note=Retained in the cytoplasm via interaction with GNAZ and GNAI2 (PubMed:10906137). Interaction with SIX1, SIX2, SIX4 or SIX5 is required for translocation to the nucleus (PubMed:10906137, PubMed:12500905).

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

EYA2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EYA2 antibody detected the EYA2 protein (arrow).

Western blot analysis of EYA2 (arrow) using rabbit polyclonal EYA2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EYA2 gene.