产品名称
DDX6 Rabbit Polyclonal Antibody (C-term)
别名
Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK
Human Gene ID
NP_001244120.1;NP_004388.2
Human Swissprot No.
P26196
特异性
This DDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-483 amino acids from the C-terminal region of human DDX6.
背景介绍
This gene encodes a member of the DEAD box protein family.
The protein is an RNA helicase found in P-bodies and stress
granules, and functions in translation suppression and mRNA
degradation. It is required for microRNA-induced gene silencing.
组织表达
Abundantly expressed in most tissues.
细胞定位
Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism (PubMed:28216671). Upon cellular stress, relocalizes to stress granules (PubMed:26184334).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
