产品名称
NCDN Rabbit Polyclonal Antibody (N-term)
别名
Neurochondrin, NCDN, KIAA0607
Human Gene ID
NP_001014839.1;NP_001014841.1;NP_055099.1
Human Swissprot No.
Q9UBB6
特异性
This NCDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-144 amino acids from the N-terminal region of human NCDN.
背景介绍
This gene encodes a leucine-rich cytoplasmic protein,
which is highly similar to a mouse protein that negatively
regulates Ca/calmodulin-dependent protein kinase II phosphorylation
and may be essential for spatial learning processes. Several
alternatively spliced transcript variants of this gene have been
described.
组织表达
Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. Weakly expressed in ovary, testis, fetal brain and small intestine
细胞定位
Cytoplasm, cytosol. Endosome membrane {ECO:0000250|UniProtKB:O35095}; Lipid-anchor. Cell projection, dendrite {ECO:0000250|UniProtKB:O35095}. Cell junction, synapse, postsynapse {ECO:0000250|UniProtKB:O35095}. Note=Localizes to somatic regions of neurons. Localization to endosome membrane requires palmitoylation {ECO:0000250|UniProtKB:O35095}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
