产品名称
TTC8 Rabbit Polyclonal Antibody (N-term)
别名
Tetratricopeptide repeat protein 8, TPR repeat protein 8, Bardet-Biedl syndrome 8 protein, TTC8, BBS8
Human Gene ID
NP_653197.2;NP_938051.1;NP_938052.1
Human Swissprot No.
Q8TAM2
特异性
This TTC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human TTC8.
背景介绍
This gene encodes a protein that has been directly linked
to Bardet-Biedl syndrome. The primary features of this syndrome
include retinal dystrophy, obesity, polydactyly, renal
abnormalities and learning disabilities. Experimentation in
non-human eukaryotes suggests that this gene is expressed in
ciliated cells and that it is involved in the formation of cilia.
Alternate transcriptional splice variants have been characterized.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cell projection, cilium {ECO:0000250|UniProtKB:Q8VD72}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
