BD-PB1560

PLEKHF2 Rabbit Polyclonal Antibody (Center)

Pleckstrin homology domain-containing family F member 2, PH domain-containing family F member 2, Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains, EAPF, PH and FYVE domain-containing protein 2, Phafin-2, Phafin2, Zinc finger FYVE domain-containing protein 18, PLEKHF2, ZFYVE18

常规抗体

WB

Human

NP_078889.1

Q9H8W4

This PLEKHF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human PLEKHF2.

WB~~1:1000

28kDa

Rabbit Ig

PLEKHF2 (Phafin 2) is a PH and FYVE domain containing protein 2. The FYVE domain and Zinc binding domain targets proteins to membrane lipids via interaction with phosphatidylinositol 3 phosphate, PI3P. The FYVE domain and Zinc binding domain present in Fab1, YOTB, Vac1, and EEA1.

Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.

Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots (PubMed:19995552). May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467).

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.