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H2BFWT Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1544
产品名称
H2BFWT Rabbit Polyclonal Antibody (Center)
别名
Histone H2B type W-T, H2B histone family member W testis-specific, H2BFWT
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001002916.3
Human Swissprot No.
Q7Z2G1
特异性
This H2BFWT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-88 amino acids from the Central region of human H2BFWT.
稀释度
WB~~1:1000
预测分子量
20kDa
同种型
Rabbit Ig
背景介绍
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.
组织表达
Testis-specific. Present in sperm cells (at protein level).
细胞定位
Nucleus membrane. Chromosome
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-H2BFWT Antibody (Center) at 1:1000 dilution + human testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 20 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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