产品名称
FNBP1L Rabbit Polyclonal Antibody (Center)
别名
Formin-binding protein 1-like, Transducer of Cdc42-dependent actin assembly protein 1, Toca-1, FNBP1L, C1orf39, TOCA1
Human Gene ID
NP_001020119.1;NP_001157945.1;NP_060207.2
Human Swissprot No.
Q5T0N5
特异性
This FNBP1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of human FNBP1L.
背景介绍
The protein encoded by this gene binds to both CDC42 and
N-WASP. This protein promotes CDC42-induced actin polymerization by
activating the N-WASP-WIP complex and, therefore, is involved in a
pathway that links cell surface signals to the actin cytoskeleton.
Alternative splicing results in multiple transcript variants
encoding different isoforms.
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.