产品名称
HUS1B Rabbit Polyclonal Antibody
蛋白名称
Checkpoint protein HUS1B (hHUS1B)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8NHY5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NHY5/entry
Mouse Swissprot No.
Q8K572
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K572
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
HUS1B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008],
组织表达
Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.
细胞定位
nucleolus,checkpoint clamp complex,site of double-strand break,
功能
similarity:Belongs to the HUS1 family.,subunit:Interacts with RAD1 and RAD9B.,tissue specificity:Expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
