产品名称
GAB3 Rabbit Polyclonal Antibody (N-term)
别名
GRB2-associated-binding protein 3, GRB2-associated binder 3, Growth factor receptor bound protein 2-associated protein 3, GAB3
Human Gene ID
NP_001075042.1;NP_542179.1
Human Swissprot No.
Q8WWW8
特异性
This GAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human GAB3.
背景介绍
GAB3 is a member of the GRB2-associated binding
protein gene family. These proteins are scaffolding/docking
proteins that are involved in several growth factor and cytokine
signaling pathways, and they contain a pleckstrin homology domain,
and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The
protein encoded by this gene facilitates macrophage
differentiation. Two transcript variants encoding different
isoforms have been found for this gene.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
