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RBBP7 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1497
产品名称
RBBP7 Rabbit Polyclonal Antibody (Center)
别名
Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001185648.1;NP_002884.1
Human Swissprot No.
Q16576
特异性
This RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human RBBP7.
稀释度
WB~~1:1000
预测分子量
48kDa
同种型
Rabbit Ig
背景介绍
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
细胞定位
Nucleus.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

RBBP7 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).

Western blot analysis of RBBP7 (arrow) using rabbit polyclonal RBBP7 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.

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