产品名称
BTN2A1 Rabbit Polyclonal Antibody (C-term)
别名
Butyrophilin subfamily 2 member A1, BTN2A1, BT21, BTF1
Human Gene ID
NP_001184162.1;NP_001184163.1;NP_008980.1;NP_510961.1
Human Swissprot No.
Q7KYR7
特异性
This BTN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human BTN2A1.
背景介绍
BTN2A1 is a member of the BTN2 subfamily of genes,
which encode proteins belonging to the butyrophilin protein family.
The gene is located in a cluster on chromosome 6, consisting of
seven genes belonging to the expanding B7/butyrophilin-like group,
a subset of the immunoglobulin gene superfamily. The encoded
protein is an integral plasma membrane B box protein involved in
lipid, fatty-acid and sterol metabolism. Multiple alternatively
spliced transcript variants encoding different isoforms have been
found for this gene.
组织表达
Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.
细胞定位
Membrane; Single-pass type I membrane protein
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.