BD-PB1491-THOC1 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

THOC1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB1491

产品名称

THOC1 Rabbit Polyclonal Antibody (C-term)

别名

THO complex subunit 1, Tho1, Nuclear matrix protein p84, p84N5, hTREX84, THOC1, HPR1

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_005122.2

Human Swissprot No.

Q96FV9

特异性

This THOC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the C-terminal region of human THOC1.

稀释度

WB~~1:1000

预测分子量

76kDa

同种型

Rabbit Ig

背景介绍

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).

组织表达

Ubiquitous. Expressed in various cancer cell lines. Expressed at very low levels in normal breast epithelial cells and highly expressed in breast tumors. Expression is strongly associated with an aggressive phenotype of breast tumors and expression correlates with tumor size and the metastatic state of the tumor progression

细胞定位

[Isoform 1]: Nucleus speckle. Nucleus, nucleoplasm. Nucleus matrix. Cytoplasm. Note=Can shuttle between the nucleus and cytoplasm. Nuclear localization is required for induction of apoptotic cell death. Translocates to the cytoplasm during the early phase of apoptosis execution

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

THOC1 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the THOC1 antibody detected the THOC1 protein (arrow).

Western blot analysis of THOC1 (arrow) using rabbit polyclonal THOC1 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the THOC1 gene.