BD-PB1481-Mouse Cdk1 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

Mouse Cdk1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB1481

产品名称

Mouse Cdk1 Rabbit Polyclonal Antibody (C-term)

别名

Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, Cdk1, Cdc2, Cdc2a, Cdkn1

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

P11440

Mouse Gene ID

NP_031685.2

特异性

This Mouse Cdk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-297 amino acids from the C-terminal region of mouse Cdk1.

稀释度

WB~~1:1000

预测分子量

34kDa

同种型

Rabbit Ig

背景介绍

Cdk1 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

细胞定位

Nucleus. Cytoplasm. Mitochondrion. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with SIRT2 on centrosome during prophase and on splindle fibers during metaphase of the mitotic cell cycle (By similarity). Cytoplasmic during the interphase. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of lysates from A431, SK-BR-3 cell line (from left to right), using Mouse Cdk1 Antibody (C-term). BD-PB1481 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Mouse Cdk1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Cdk1 antibody detected the Cdk1 protein (arrow).

Mouse Cdk1 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Cdk1 antibody detected the Cdk1 protein (arrow).