产品名称
SNX2 Rabbit Polyclonal Antibody (C-term)
别名
Sorting nexin-2, Transformation-related gene 9 protein, TRG-9, SNX2
Human Gene ID
NP_001265128.1;NP_003091.2
Human Swissprot No.
O60749
特异性
This SNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-485 amino acids from the C-terminal region of human SNX2.
背景介绍
This gene encodes a member of the sorting nexin family.
Members of this family contain a phox (PX) domain, which is a
phosphoinositide binding domain, and are involved in intracellular
trafficking. This protein associates with formin-binding protein
17, but its function is unknown. This protein may form oligomeric
complexes with family members.
细胞定位
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium Note=Colocalized with SORT1 to tubular endosomal membrane structures called endosome-to-TGN transport carriers (ETCs) which are budding from early endosome vacuoles just before maturing into late endosome vacuoles (PubMed:18088323). Colocalized with F-actin at the leading edge of lamellipodia in cells in a KALRN-dependent manner (PubMed:20604901).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
