产品名称
Mouse Cdk4 Rabbit Polyclonal Antibody (C-term)
别名
Cyclin-dependent kinase 4, CRK3, Cell division protein kinase 4, PSK-J3, Cdk4, Crk3
Human Swissprot No.
P30285
Mouse Gene ID
NP_034000.1
特异性
This Mouse Cdk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-246 amino acids from the C-terminal region of mouse Cdk4.
背景介绍
Cdk4 is probably involved in the control of the cell cycle.
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:P11802}. Nucleus {ECO:0000250|UniProtKB:P11802}. Nucleus membrane {ECO:0000250|UniProtKB:P11802}. Note=Cytoplasmic when non-complexed Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) to S phase. Also present in nucleoli and heterochromatin lumps. Colocalizes with RB1 after release into the nucleus (By similarity). {ECO:0000250|UniProtKB:P11802}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.