产品名称
COPS8 Rabbit Polyclonal Antibody (N-term)
别名
COP9 signalosome complex subunit 8, SGN8, Signalosome subunit 8, COP9 homolog, hCOP9, JAB1-containing signalosome subunit 8, COPS8, CSN8
Human Gene ID
NP_006701.1;NP_937832.1
Human Swissprot No.
Q99627
特异性
This COPS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human COPS8.
背景介绍
The protein encoded by this gene is one of the eight
subunits of COP9 signalosome, a highly conserved protein complex
that functions as an important regulator in multiple signaling
pathways. The structure and function of COP9 signalosome is similar
to that of the 19S regulatory particle of 26S proteasome. COP9
signalosome has been shown to interact with SCF-type E3 ubiquitin
ligases and act as a positive regulator of E3 ubiquitin ligases.
Alternatively spliced transcript variants encoding distinct
isoforms have been observed.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
