产品名称
Mouse Frk Rabbit Polyclonal Antibody (C-term)
别名
Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
Human Swissprot No.
Q922K9
Mouse Gene ID
NP_001153016.1;NP_034367.2
特异性
This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.
背景介绍
Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
组织表达
Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung
细胞定位
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
