产品名称
Mouse Tec Rabbit Polyclonal Antibody (Center)
别名
Tyrosine-protein kinase Tec, Tec
Human Swissprot No.
P24604
Mouse Gene ID
NP_001106931.1;NP_001106932.1;NP_001106935.1
特异性
This Mouse Tec antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-205 amino acids from the Central region of mouse Tec.
背景介绍
Tec may be an important signal transducer for cell division and/or for differentiation in the liver system.
组织表达
Preferentially expressed in liver. Expression is also seen in the hematopoietic cells such as bone marrow, thymus and spleen. Lower expression is seen in the heart, kidney and ovary
细胞定位
Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Following B-cell or T-cell receptors activation by antigen, translocates to the plasma membrane through its PH domain. Thrombin and integrin engagement induces translocation of TEC to the cytoskeleton during platelet activation. In cardiac myocytes, assumes a diffuse intracellular localization under basal conditions but is recruited to striated structures upon various stimuli, including ATP (By similarity).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
