BD-PB1405-ALDH5A1 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

ALDH5A1 Rabbit Polyclonal Antibody (C-term)

产品详情相关文献产品问答相关产品

产品基本信息

产品货号

BD-PB1405

产品名称

ALDH5A1 Rabbit Polyclonal Antibody (C-term)

别名

Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, ALDH5A1, SSADH

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001071.1;NP_733936.1

Human Swissprot No.

P51649

特异性

This ALDH5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-398 amino acids from the C-terminal region of human ALDH5A1.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

57kDa

同种型

Rabbit Ig

背景介绍

ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.

组织表达

Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta

细胞定位

Mitochondrion.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of ALDH5A1 Antibody (C-term) in SK-BR-3 cell line lysates (35ug/lane). ALDH5A1(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with *ALDH5A1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.