产品名称
Mouse Mos Rabbit Polyclonal Antibody (C-term)
别名
Proto-oncogene serine/threonine-protein kinase mos, Oocyte maturation factor mos, Proto-oncogene c-Mos, Mos
Human Swissprot No.
P00536
特异性
This Mouse Mos antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-329 amino acids from the C-terminal region of mouse Mos.
背景介绍
MOS is a proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation.
组织表达
Expressed specifically in testis during spermatogenesis
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
