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MIPEP Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB1378
产品名称
MIPEP Rabbit Polyclonal Antibody (Center)
别名
Mitochondrial intermediate peptidase, MIP, MIPEP, MIP
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_005923.2
Human Swissprot No.
Q99797
特异性
This MIPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the Central region of human MIPEP.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
81kDa
同种型
Rabbit Ig
背景介绍
MIPEP performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. It may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia.
细胞定位
Mitochondrion matrix.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of anti-MIPEP Antibody (Center) in 293 cell line lysates (35ug/lane). MIPEP (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MIPEP antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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