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SEC23IP Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB1363
产品名称
SEC23IP Rabbit Polyclonal Antibody (C-term)
别名
SEC23-interacting protein, p125, SEC23IP
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_009121.1
Human Swissprot No.
Q9Y6Y8
特异性
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
稀释度
WB~~1:1000
预测分子量
111kDa
同种型
Rabbit Ig
背景介绍
COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway. [provided by RefSeq].
组织表达
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle
细胞定位
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

SEC23IP Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SEC23IP antibody detected the SEC23IP protein (arrow).

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