产品名称
SEC23IP Rabbit Polyclonal Antibody (C-term)
别名
SEC23-interacting protein, p125, SEC23IP
Human Gene ID
NP_009121.1
Human Swissprot No.
Q9Y6Y8
特异性
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
背景介绍
COPII-coated vesicles are involved in protein transport
from the endoplasmic reticulum to the Golgi apparatus. The protein
encoded by this gene was identified by its interaction with a mouse
protein similar to yeast Sec23p, an essential component of the
COPII. This protein shares significant similarity with
phospholipid-modifying proteins, especially phosphatidic acid
preferring-phospholipase A1. Overexpression of this protein has
been shown to cause disorganization of the endoplasmic
reticulum-Golgi intermediate compartment and Golgi apparatus, which
suggests its role in the early secretory pathway. [provided by
RefSeq].
组织表达
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle
细胞定位
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.