产品名称
ZIC4 Rabbit Polyclonal Antibody (N-term)
别名
Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4, ZIC4
Human Gene ID
NP_001161850.1;NP_001161851.1;NP_001230185.1;NP_115529.2
Human Swissprot No.
Q8N9L1
特异性
This ZIC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ZIC4.
背景介绍
This gene encodes a member of the ZIC family of C2H2-type
zinc finger proteins. Members of this family are important during
development, and have been associated with X-linked visceral
heterotaxy and holoprosencephaly type 5. This gene is closely
linked to the gene encoding zinc finger protein of the cerebellum
1, a related family member on chromosome 3. Heterozygous deletion
of these linked genes is involved in Dandy-Walker malformation,
which is a congenital cerebellar malformation. Multiple transcript
variants have been identified for this gene.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.