BD-PB1346-POTE Rabbit Polyclonal Antibody (C-term L446)-现货抗体产品库武汉枢密脑科学技术有限公司

POTE Rabbit Polyclonal Antibody (C-term L446)

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产品基本信息

产品货号

BD-PB1346

产品名称

POTE Rabbit Polyclonal Antibody (C-term L446)

别名

POTE ankyrin domain family member D, ANKRD26-like family B member 3, Ankyrin repeat domain-containing protein 21, Prostate, ovary, testis-expressed protein, Protein POTE, POTED, A26B3, ANKRD21, POTE

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001244291.1;NP_778146.2

Human Swissprot No.

Q86YR6

特异性

This POTE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438~468 amino acids from the C-term region of human POTE.

稀释度

WB~~1:500;IHC-P~~1:100~500

预测分子量

66kDa

同种型

Rabbit Ig

背景介绍

POTE, is a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer. The POTE protein contains seven ankyrin repeats between amino acids 140 and 380. Expression of POTE in prostate cancer and its undetectable expression in normal essential tissues make POTE a candidate for the immunotherapy of prostate cancer. The existence of a large number of closely related but rapidly diverging members, their location on multiple chromosomes and their limited expression pattern suggest an important role for the POTE gene family in reproductive processes.

组织表达

Expressed in prostate, ovary, testis, placenta and prostate cancer cell lines. Localizes to basal and terminal prostate epithelial cells.

细胞定位

Cell membrane; Peripheral membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-POTE Antibody (C-term L446) at 1:500 dilution Lane 1: human ovary lysate Lane 2: human testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 66 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with POTE antibody (C-term L446), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.