产品名称
XCR1 Rabbit Polyclonal Antibody
蛋白名称
Chemokine XC receptor 1 (G-protein coupled receptor 5) (Lymphotactin receptor) (XC chemokine receptor 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P46094
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P46094/entry
Mouse Swissprot No.
Q9R0M1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R0M1
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
XCR1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
G-protein coupled receptors,Spleen,
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Cytokine-cytokine receptor interaction;Chemokine;
功能
function:Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.