BD-PB1335

PADI2 Rabbit Polyclonal Antibody (C-term)

Protein-arginine deiminase type-2, PAD-H19, Peptidylarginine deiminase II, Protein-arginine deiminase type II, PADI2, KIAA0994, PDI2

常规抗体

WB

Human

NP_031391.2

Q9Y2J8

This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2.

WB~~1:1000

76kDa

Rabbit Ig

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq].

Detected in keratinocytes in epidermis (at protein level).

Cytoplasm.

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.